Leptin is a hormone that makes you feel full. Leptin was only discovered in 1994, and scientists are still working to understand what leptin's role is. In most people the function of leptin is to ...

Ever wondered why sometimes you feel like you could eat a horse or why those cravings just won't quit, even when you're ...

Defects in POMC-expressing neurons are also known to cause leptin resistance and obesity, Friedman notes, adding, “it was satisfying to find that an acquired form of leptin resistance targets this ...

Leptin resistance in obesity. Leptin interacts with specific leptin receptors to inhibit excess feeding and its elevation and obesity is therefore often thought to indicate a leptin resistant state.

Leptin resistance can be identified through key markers, such as leptin-receptor mRNA and protein levels, which indicate how effectively the body is responding to leptin.

For years, scientists have pointed to leptin resistance as a possible cause of obesity. Research, however, has found that leptin action isn't the culprit. Leptin is a hormone that plays a role in ...

OBJECTIVE: To examine the determinants of plasma leptin levels and leptin resistance in a sample of extremely obese subjects and their relatives. DESIGN and METHOD: We obtained plasma leptin ...

Resistance to leptin, a protein that plays a key role in regulating metabolism and appetite, may help prevent the development of acute respiratory distress syndrome (ARDS) and acute lung injury ...