Leptin is a hormone that makes you feel full. Leptin was only discovered in 1994, and scientists are still working to understand what leptin's role is. In most people the function of leptin is to ...

Ever wondered why sometimes you feel like you could eat a horse or why those cravings just won't quit, even when you're ...

Defects in POMC-expressing neurons are also known to cause leptin resistance and obesity, Friedman notes, adding, “it was satisfying to find that an acquired form of leptin resistance targets this ...

Leptin resistance in obesity. Leptin interacts with specific leptin receptors to inhibit excess feeding and its elevation and obesity is therefore often thought to indicate a leptin resistant state.

Leptin resistance can be identified through key markers, such as leptin-receptor mRNA and protein levels, which indicate how effectively the body is responding to leptin.

Obesity, Leptin Resistance, and Metabolic Syndrome. MS, defined by a constellation of high blood pressure, elevated triglycerides, insulin resistance, and abdominal obesity, ...

Researchers once hoped they could invent a drug increasing a hormone called leptin that would suppress appetite and reduce obesity. But they ran into a brick wall called “leptin resistance” and moved ...