RMD Open7d
Holistic approaches in systemic lupus erythematosus: do physicians avoid addressing difficult-to-treat but highly relevant symptoms?
Despite advancements in the management of systemic lupus erythematosus (SLE), patients experience poor health-related quality of life (hrQoL) and premature death due to disease severity and treatment ...
rmdopen.bmj12d
Hyaluronan for knee osteoarthritis: an updated meta-analysis of trials with low risk of bias
Background The effectiveness of intra-articular hyaluronic acid (IAHA) injection for knee osteoarthritis (KOA) is debated. Objectives To evaluate the effect of IAHA for patients with KOA by analysing ...
rmdopen.bmj10d
Cartilage-gut-microbiome axis: a new paradigm for novel therapeutic opportunities in osteoarthritis
DNA of gut microbiota can be found in synovium of osteoarthritis and rheumatoid arthritis. This finding could result from the translocation of still alive bacteria from gut to joints through blood, ...
rmdopen.bmj12d
Humoral and cellular SARS-CoV-2 vaccine responses in patients with giant cell arteritis and polymyalgia rheumatica
Objectives Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are overlapping autoinflammatory diseases affecting people over 50 years. The diseases are treated with immunosuppressive drugs ...
rmdopen.bmj10d
Spontaneous resolution of acute gout: mechanisms and therapeutic targets
3 Jiangxi Provincial Clinical Research Center for Rheumatic and Immunologic Diseases, Nanchang, People's Republic of China 4 Key Laboratory of Rheumatology and Immunology, Health Commission of Jiangxi ...
rmdopen.bmj10d
New pro-inflammatory cytokine IL-40 is produced by activated neutrophils and plays a role in the early stages of seropositive rheumatoid arthritis
Objective Interleukin (IL)-40 is a new cytokine related to immune system function and malignancies. Recently, an association of IL-40 with rheumatoid arthritis (RA) and externalisation of neutrophil ...
rmdopen.bmj10d
Procedures for the content, conduct and format of EULAR/PReS paediatric musculoskeletal ultrasound courses
Background Despite the worldwide increasing request of education on paediatric musculoskeletal ultrasound (PedMSUS), content, conduct and format of PedMSUS courses have never been internationally ...
rmdopen.bmj11d
Prevalence and consequences of psoriasis in recent axial spondyloarthritis: an analysis of the DESIR cohort over 6 years
Objectives The consequences of psoriasis associated to axial spondyloarthritis (axSpA) are unclear. The objectives were to determine the prevalence and the consequences of psoriasis in recent axSpA ...
rmdopen.bmj9d
Patient appropriateness for total knee arthroplasty and predicted probability of a good outcome
Objectives One-fifth of total knee arthroplasty (TKA) recipients experience a suboptimal outcome. Incorporation of patients’ preferences in TKA assessment may improve outcomes. We determined the ...
rmdopen.bmj13d
4-year results from the RAPID-PsA phase 3 randomised placebo-controlled trial of certolizumab pegol in psoriatic arthritis
Objective To report the efficacy, patient-reported, radiographic and safety outcomes of 4 years’ certolizumab pegol (CZP) treatment in patients with psoriatic arthritis (PsA). Methods RAPID-PsA ...
rmdopen.bmj10d
Upadacitinib therapy in refractory inflammatory myositis: a case series of 10 patients
Objectives To evaluate the effectiveness and safety of upadacitinib in treatment-refractory inflammatory myositis. Methods Patients with refractory inflammatory myositis treated with upadacitinib from ...
rmdopen.bmj12d
Secukinumab does not impair the immunogenic response to the influenza vaccine in patients
Objective To evaluate whether immunological response to influenza vaccination is impaired in patients who are receiving secukinumab. Patients and methods Subjects suffering from psoriatic arthritis or ...