The enzyme transhydrogenase plays a central role in regulating metabolic processes in animals and humans alike. Malfunction can lead to serious disorders. For the first time, structural biologists ...

Researchers from Tokyo Metropolitan University have developed a new structure determination method using nuclear magnetic resonance (NMR) spectroscopy which shows how different parts of complex ...

Researchers have used cryo- electron microscopy to elucidate for the first time the structure and function of a very small enzyme embedded in cell membranes. This enzyme builds complex sugar trees ...

Chemical structure for thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and xylulose 5-phosphate substrate in black. Credit: Thomas ...

Scientists at St. Jude Children's Research Hospital have discovered how a single enzyme called E1 performs a rapid-fire, three-part chemical makeover of a protein that helps control some of the most ...

Acetolactate synthase, also known as acetohydroxyacid synthase (AHAS), is an enzyme involved in the branched chain amino acid biosynthesis pathway. AHAS is a thiamine diphosphate (ThDP)-dependent ...

David Cantu and Tin Nguyen have received a 3-year, $599,999 grant from the National Science Foundation’s Cyberinfrastructure for Sustained Scientific Innovation (CSSI) Program to support the creation ...

Background and aims Aluminum is a major deleterious factor for soybean productivity in acidic soils. Soil enzyme activities and bacteria play important roles in improving the stress tolerance of ...

Within each cell, the power houses called mitochondria continuously break down molecules derived from food to generate energy as well as to produce new molecules that serve as building blocks of cells ...

Researchers from Tokyo Metropolitan University have developed a new structure determination method using Nuclear Magnetic Resonance (NMR) spectroscopy which shows how different parts of complex ...