Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though ...

Researchers say study findings have important implications for our understanding of the pathogenesis of obesity and potential therapeutic applications.

Though, keep in mind that you never lose fat cells. They just get smaller. Obesity can lead to leptin resistance, which makes it harder to feel full. But it’s not always about body fat.

Despite consistent workouts and healthy eating, hormonal imbalances might be sabotaging your weight loss. Discover which ...

A paper published in the May issue of Diabetes implicates triglycerides in the mechanism of leptin resistance. These fats, elevated in obesity, are what disrupt the transport of the hormone across the ...

In humans, many leptin deficiency syndromes are responsive to leptin replacement therapy. As leptin is involved in numerous pathways, the effects of too little leptin are widespread (including ...

Higher leptin levels were associated with chronic widespread pain among patients with RA, even after adjusting for age, BMI, and sex.

However, there may be circumstances where a person develops a resistance to leptin, weakening the body’s reactivity to the hormone. This unfavourable circumstance could result in overeating ...

However, daily leptin shots are both expensive -- costing ... as it improves insulin resistance. Tirzepatide is administered through a weekly injection, potentially reducing the burden and pain ...